Erp44tm1c(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Erp44tm1c(KOMP)Wtsi |
Name: |
endoplasmic reticulum protein 44; targeted mutation 1c, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:6856614 |
Gene: |
Erp44 Location: Chr4:48193323-48279558 bp, - strand Genetic Position: Chr4, 26.09 cM
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Alliance: |
Erp44tm1c(KOMP)Wtsi page
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IMPC: |
Erp44 gene page |
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Mutant Cell Line: |
EPD0818_1_A11 |
Germline Transmission: |
Earliest citation of germline transmission:
J:94077
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
Vector: L1L2_st0
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Mutation details: The L1L2_st0 cassette was inserted at position 48244027 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 48244027. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:94077)
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Original: |
J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015; |
All: |
1 reference(s) |
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