Il17ra^em1Hgh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il17ra^em1Hgh
• Name: interleukin 17 receptor A; endonuclease-mediated mutation 1, Homayon Ghiasi
• MGI ID: MGI:6850130
• Gene: Il17ra Location: Chr6:120440143-120460692 bp, + strand Genetic Position: Chr6, 56.95 cM
• Alliance: Il17ra^em1Hgh page

Mutation origin

• Strain of Origin: B6N.129S5(B6)-Il17rc^tm1Lex/Mmucd

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 3409 bp spanning exon 5 through 9. (J:293006)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Il17ra Mutation: 46 strains or lines available

Notes

This allele was generated in fertilized eggs containing Il17rc^tm1Lex.

References

• Original: J:293006 Hirose S, et al., Role of TH17 Responses in Increasing Herpetic Keratitis in the Eyes of Mice Infected with HSV-1. Invest Ophthalmol Vis Sci. 2020 Jun 3;61(6):20
• All: 2 reference(s)