Nr1d1^em1Dwry
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nr1d1^em1Dwry
• Name: nuclear receptor subfamily 1, group D, member 1; endonuclease-mediated mutation 1, David W Ray
• MGI ID: MGI:6850059
• Synonyms: Reverbalpha^Flox2-6
• Gene: Nr1d1 Location: Chr11:98658758-98666159 bp, - strand Genetic Position: Chr11, 62.66 cM
• Alliance: Nr1d1^em1Dwry page

Mutation origin

• Strain of Origin: (C57BL/6NHsd x DBA/2NHsd)F1

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2 through 6. (J:296724)

Expression

In Mice Carrying this Mutation:

205440 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr1d1 Mutation: 44 strains or lines available

References

• Original: J:296724 Hunter AL, et al., Nuclear receptor REVERBalpha is a state-dependent regulator of liver energy metabolism. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25869-25879
• All: 2 reference(s)