Cisd1^tm1.1Kins
Targeted Allele Detail

Summary

• Symbol: Cisd1^tm1.1Kins
• Name: CDGSH iron sulfur domain 1; targeted mutation 1.1, Shintaro Kinugawa
• MGI ID: MGI:6850047
• Synonyms: mitoNEET flox
• Gene: Cisd1 Location: Chr10:71166324-71180679 bp, - strand Genetic Position: Chr10, 36.88 cM
• Alliance: Cisd1^tm1.1Kins page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317176
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:317176)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cisd1 Mutation: 15 strains or lines available

References

• Original: J:317176 Furihata T, et al., Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure. Commun Biol. 2021 Jan 29;4(1):138
• All: 1 reference(s)