Gt(ROSA)26Sor^{em2(CAG-Rnf6,-EGFP)Cya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em2(CAG-Rnf6,-EGFP)Cya}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:6849760
• Synonyms: Gt(ROSA)26Sor^{em2(CAG-Rnf6,-EGFP)Cgen}, Rnf6 tg
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em2(CAG-Rnf6,-EGFP)Cya} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted into the locus the CAG promoter, floxed stop cassette, gene sequence, IRES sequence, and EGFP reporter gene. (J:316088)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:316088 Xu H, et al., RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2. Oncogene. 2021 Nov;40(47):6513-6526
• All: 1 reference(s)