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Cdk2ap1em1Linhe
Endonuclease-mediated Allele Detail
Summary
Symbol: Cdk2ap1em1Linhe
Name: cyclin dependent kinase 2 associated protein 1; endonuclease-mediated mutation 1, Lin He
MGI ID: MGI:6841009
Synonyms: Cdk2ap1deltaCAN
Gene: Cdk2ap1  Location: Chr5:124483502-124492691 bp, - strand  Genetic Position: Chr5, 63.53 cM
Alliance: Cdk2ap1em1Linhe page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Modified isoform(s))
Mutation:    Intragenic deletion
    The targeting construct deleted exon 1. The allele fails to produce the canonical isoform. (J:312811)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdk2ap1 Mutation:  62 strains or lines available
References
Original:  J:312811 Modzelewski AJ, et al., A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. Cell. 2021 Oct 28;184(22):5541-5558.e22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory