Cdk2ap1^em1Linhe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdk2ap1^em1Linhe
• Name: cyclin dependent kinase 2 associated protein 1; endonuclease-mediated mutation 1, Lin He
• MGI ID: MGI:6841009
• Synonyms: Cdk2ap1^deltaCAN
• Gene: Cdk2ap1 Location: Chr5:124483502-124492691 bp, - strand Genetic Position: Chr5, 63.53 cM
• Alliance: Cdk2ap1^em1Linhe page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s))
• Mutation: Intragenic deletion
• The targeting construct deleted exon 1. The allele fails to produce the canonical isoform. (J:312811)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cdk2ap1 Mutation: 62 strains or lines available

References

• Original: J:312811 Modzelewski AJ, et al., A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. Cell. 2021 Oct 28;184(22):5541-5558.e22
• All: 1 reference(s)