Cd300lf^em2Cbwi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd300lf^em2Cbwi
• Name: CD300 molecule like family member F; endonuclease-mediated mutation 2, Craig Wilen
• MGI ID: MGI:6838374
• Synonyms: Cd300lf^F
• Gene: Cd300lf Location: Chr11:115007040-115024818 bp, - strand Genetic Position: Chr11, 80.59 cM
• Alliance: Cd300lf^em2Cbwi page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 endonuclease-mediated genome editing was used to insert loxP sites in intron 2 and intron 3. Exon 3 encodes amino acids 129 to 158 in the ectodomain. (J:316412)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cd300lf Mutation: 23 strains or lines available

References

• Original: J:316412 Graziano VR, et al., CD300lf Conditional Knockout Mouse Reveals Strain-Specific Cellular Tropism of Murine Norovirus. J Virol. 2021 Jan 13;95(3)
• All: 2 reference(s)