Oscp1^tm1.1Bxi
Targeted Allele Detail

Summary

• Symbol: Oscp1^tm1.1Bxi
• Name: organic solute carrier partner 1; targeted mutation 1.1, Bo Xiang
• MGI ID: MGI:6836770
• Synonyms: NOR1^-
• Gene: Oscp1 Location: Chr4:125952358-125985988 bp, + strand Genetic Position: Chr4, 59.82 cM
• Alliance: Oscp1^tm1.1Bxi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314639
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked PGK-neomycin selection cassette replaced exons 3 to 5. The selection cassette was removed via flp-mediated recombination. (J:314639)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oscp1 Mutation: 38 strains or lines available

References

• Original: J:314639 Chen S, et al., Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma. J Cell Physiol. 2018 Jun;233(6):5002-5013
• All: 1 reference(s)