Pex10^em3Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pex10^em3Lutzy
• Name: peroxisomal biogenesis factor 10; endonuclease-mediated mutation 3, Cathy Lutz
• MGI ID: MGI:6836731
• Synonyms: Pex10^indel
• Gene: Pex10 Location: Chr4:155151487-155156863 bp, + strand Genetic Position: Chr4, 86.17 cM
• Alliance: Pex10^em3Lutzy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 genome editing generated a 1 nt insertion followed immediately by the 3 nt deletion (indel mutation). This net 2 nt deletion is predicted to cause a frameshift at Cys-286 for 71 amino acids and terminating at a TAA stop codon positioned within the 3' UTR. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pex10 Mutation: 15 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)