Ccl7^em5Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccl7^em5Gpt
• Name: C-C motif chemokine ligand 7; endonuclease-mediated mutation 5, GemPharmatech Co., Ltd
• MGI ID: MGI:6834776
• Synonyms: Ccl7^em5Cd1902
• Gene: Ccl7 Location: Chr11:81936538-81938351 bp, + strand Genetic Position: Chr11, 49.83 cM
• Alliance: Ccl7^em5Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 1902 bp. (J:314009)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccl7 Mutation: 12 strains or lines available

References

• Original: J:314009 Xue J, et al., Astrocyte-derived CCL7 promotes microglia-mediated inflammation following traumatic brain injury. Int Immunopharmacol. 2021 Oct;99:107975
• All: 1 reference(s)