Cyp2c23^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Cyp2c23^tm1.1Arte
• Name: cytochrome P450, family 2, subfamily c, polypeptide 23; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6834773
• Gene: Cyp2c23 Location: Chr19:43993461-44017647 bp, - strand Genetic Position: Chr19, 36.69 cM
• Alliance: Cyp2c23^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288489
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted a loxP and an F3 site upstream of exon 3 and an FRT site and loxP site downstream of exon 3. Flp-mediated recombination removed the selection cassettes and left exon 5 floxed. Cre-mediated recombination removed exons 3 through 5. (J:288489)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cyp2c23 Mutation: 28 strains or lines available

References

• Original: J:288489 Hu J, et al., Role of Muller cell cytochrome P450 2c44 in murine retinal angiogenesis. Prostaglandins Other Lipid Mediat. 2017 Nov;133:93-102
• All: 4 reference(s)