Disc1^em1Kwt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Disc1^em1Kwt
• Name: disrupted in schizophrenia 1; endonuclease-mediated mutation 1, Kazuo Kuwata
• MGI ID: MGI:6833988
• Synonyms: DISC1 L604F
• Gene: Disc1 Location: Chr8:125780934-125988597 bp, + strand Genetic Position: Chr8, 73.26 cM
• Alliance: Disc1^em1Kwt page

Mutation origin

• Strain of Origin: (C57BL/6JJcl x (C57BL/6JJcl x DBA/2JJcl)F1)F1

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Disc1 Mutation: 69 strains or lines available

References

• Original: J:314277 Kakuda K, et al., A DISC1 point mutation promotes oligomerization and impairs information processing in a mouse model of schizophrenia. J Biochem. 2019 Apr 1;165(4):369-378
• All: 1 reference(s)