Havcr2tm1.1Kuch
Targeted Allele Detail
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Symbol: |
Havcr2tm1.1Kuch |
Name: |
hepatitis A virus cellular receptor 2; targeted mutation 1.1, Vijay K Kuchroo |
MGI ID: |
MGI:6833984 |
Synonyms: |
Havcr2fl |
Gene: |
Havcr2 Location: Chr11:46345762-46372082 bp, + strand Genetic Position: Chr11, 27.9 cM
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Alliance: |
Havcr2tm1.1Kuch page
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Germline Transmission: |
Earliest citation of germline transmission:
J:314511
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: The targeting construct inserted a loxP site upstream of exon 1 and an FRT-flanked neomycin resistance cassette with a 3' loxP site downstream of exon1. Flp-mediated recombination removed the selection cassette and left exon 1 floxed.
(J:314511)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Havcr2 Mutation: |
32 strains or lines available
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Original: |
J:314511 Dixon KO, et al., TIM-3 restrains anti-tumour immunity by regulating inflammasome activation. Nature. 2021 Jul;595(7865):101-106 |
All: |
1 reference(s) |
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