Sox9^tm5.1Tlu
Targeted Allele Detail

Summary

• Symbol: Sox9^tm5.1Tlu
• Name: SRY (sex determining region Y)-box 9; targeted mutation 5.1 Thomas Lufkin
• MGI ID: MGI:6831626
• Gene: Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
• Alliance: Sox9^tm5.1Tlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314899
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette inserted upstream of the translation start site in exon 1. Flp-mediated recombination removed the selection cassette. (J:314899)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox9 Mutation: 33 strains or lines available

References

• Original: J:314899 Lee WJ, et al., An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos. Biomed Res Int. 2017;2017:8932583
• All: 1 reference(s)