Gabrg2^em1Sunt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gabrg2^em1Sunt
• Name: gamma-aminobutyric acid type A receptor, subunit gamma 2; endonuclease-mediated mutation 1, Tao Sun
• MGI ID: MGI:6831624
• Synonyms: Gabrg2^fl
• Gene: Gabrg2 Location: Chr11:41801030-41891684 bp, - strand Genetic Position: Chr11, 24.8 cM
• Alliance: Gabrg2^em1Sunt page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Using CRISPR/Cas9-mediated genome engineering techniques, two loxP sites flanking exon 2 of the Gabrg2 gene transcript were inserted. (J:315771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabrg2 Mutation: 40 strains or lines available

References

• Original: J:315771 Li X, et al., Neocortex- and hippocampus-specific deletion of Gabrg2 causes temperature-dependent seizures in mice. Cell Death Dis. 2021 May 28;12(6):553
• All: 1 reference(s)