Setd2^em1Ghu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Setd2^em1Ghu
• Name: SET domain containing 2; endonuclease-mediated mutation 1, Gang Huang
• MGI ID: MGI:6831061
• Synonyms: Setd2^f
• Gene: Setd2 Location: Chr9:110361368-110447703 bp, + strand Genetic Position: Chr9, 60.0 cM
• Alliance: Setd2^em1Ghu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 6 was flanked by loxP sites using CRISPR/Cas9 technology. (J:314830)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Setd2 Mutation: 102 strains or lines available

References

• Original: J:314830 Zhou Y, et al., Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation. Haematologica. 2018 Jul;103(7):1110-1123
• All: 1 reference(s)