Tctn2^tm1.2Reit
Targeted Allele Detail

Summary

• Symbol: Tctn2^tm1.2Reit
• Name: tectonic family member 2; targeted mutation 1.2, Jeremy Reiter
• MGI ID: MGI:6827394
• Synonyms: Tctn2^lox, Tctn2^tm1cReit
• Gene: Tctn2 Location: Chr5:124736812-124765803 bp, + strand Genetic Position: Chr5, 63.68 cM, cytoband F
• Alliance: Tctn2^tm1.2Reit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176174
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A floxed puromycin selection cassette was inserted downstream of exon 3. Cre-mediated recombination removed the selection cassette. (J:176174)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tctn2 Mutation: 20 strains or lines available

Notes

The allele was originally generated in ES cells containing Tctn1^{Gt(KST296)Byg}.

References

• Original: J:176174 Garcia-Gonzalo FR, et al., A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat Genet. 2011 Aug;43(8):776-84
• All: 2 reference(s)