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Mbd2em1Wgcy
Endonuclease-mediated Allele Detail
Summary
Symbol: Mbd2em1Wgcy
Name: methyl-CpG binding domain protein 2; endonuclease-mediated mutation 1, Cong-Yi Wang
MGI ID: MGI:6825813
Synonyms: Mbd2flox
Gene: Mbd2  Location: Chr18:70701260-70759202 bp, + strand  Genetic Position: Chr18, 44.54 cM
Alliance: Mbd2em1Wgcy page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, No functional change)
Mutation:    Insertion
    CRISPR/Cas9 technology was used to flank exon 2 with loxP sites. (J:314537)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mbd2 Mutation:  21 strains or lines available
References
Original:  J:314537 Wang Y, et al., MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program. Sci Adv. 2021 Jan;7(1)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory