Pik3cg^{tm1d(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Pik3cg^{tm1d(EUCOMM)Wtsi}
• Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; targeted mutation 1d, Wellcome Trust Sanger Institute
• MGI ID: MGI:6806145
• Gene: Pik3cg Location: Chr12:32223472-32258658 bp, - strand Genetic Position: Chr12, 13.74 cM, cytoband B
• Alliance: Pik3cg^{tm1d(EUCOMM)Wtsi} page
• IMPC: Pik3cg gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:313009
• Parent Cell Line: JM8A1.N3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A null/knockout allele was created by flp and cre recombinase expression in mice carrying this allele to remove the lacZ sequence, neo selection cassette and the loxP-flanked critical exon(s). (J:313009)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pik3cg Mutation: 60 strains or lines available

References

• Original: J:313009 Zhao J, et al., ACTH treatment promotes murine cardiac allograft acceptance. JCI Insight. 2021 Jul 8;6(13)
• All: 1 reference(s)