Ptgdr^tm1.1Brey
Targeted Allele Detail

Summary

• Symbol: Ptgdr^tm1.1Brey
• Name: prostaglandin D receptor; targeted mutation 1.1, Richard M Breyer
• MGI ID: MGI:6802150
• Synonyms: DP1^flox
• Gene: Ptgdr Location: Chr14:45088692-45096832 bp, - strand Genetic Position: Chr14, 22.59 cM
• Alliance: Ptgdr^tm1.1Brey page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237274
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 1. A recombinase-flanked neomycin cassette was removed in the final allele. (J:237274)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptgdr Mutation: 30 strains or lines available

References

• Original: J:237274 Kong D, et al., PKA regulatory IIalpha subunit is essential for PGD2-mediated resolution of inflammation. J Exp Med. 2016 Sep 19;213(10):2209-26
• All: 3 reference(s)