Sycp3^em1Kee
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sycp3^em1Kee
• Name: synaptonemal complex protein 3; endonuclease-mediated mutation 1, Kehkooi Kee
• MGI ID: MGI:6791319
• Synonyms: VPHS
• Gene: Sycp3 Location: Chr10:88295449-88309098 bp, + strand Genetic Position: Chr10, 43.94 cM, cytoband C
• Alliance: Sycp3^em1Kee page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: A reporter gene cassette consisting of a monomer fluorescent protein mVenus, a P2A linker, and a copy of HA epitope tag was inserted right after the start codon of Sycp3 using CRISPR/Cas9 technology. (J:310334)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sycp3 Mutation: 17 strains or lines available

References

• Original: J:310334 Chen B, et al., IGSF11 is required for pericentric heterochromatin dissociation during meiotic diplotene. PLoS Genet. 2021 Sep;17(9):e1009778
• All: 2 reference(s)