App^em7H
Endonuclease-mediated Allele Detail

Summary

• Symbol: App^em7H
• Name: amyloid beta precursor protein; endonuclease-mediated mutation 7, Harwell
• MGI ID: MGI:6790443
• Synonyms: App^{G601R,F606Y,R609H}
• Gene: App Location: Chr16:84751236-84972187 bp, - strand Genetic Position: Chr16, 46.92 cM, cytoband C3-qter
• Alliance: App^em7H page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• CRISPR-targeting induced three substitutions (G601R, F606Y, and R609H). (J:169366)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any App Mutation: 89 strains or lines available

References

• Original: J:169366 MouseBook^TM, Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013
• All: 1 reference(s)