Tg(Ins1-rtTA)#Caoy
Transgene Detail
|
|
| Symbol: |
Tg(Ins1-rtTA)#Caoy |
| Name: |
transgene insertion, Yanan Cao |
| MGI ID: |
MGI:6790391 |
| Synonyms: |
Ins1-rtTA |
| Transgene: |
Tg(Ins1-rtTA)#Caoy Location: unknown
|
| Alliance: |
Tg(Ins1-rtTA)#Caoy page
|
|
|
|
| Transgene Type: |
|
Transgenic (Transactivator) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The transgene consists of an 8.5-kb fragment of mouse Ins1 promoter (Ins1; nucleotides -8.5 kb to +12 bp relative to the transcriptional start site), a cDNA for rtTA, and a polyadenylation signal. Five lines (1-5) were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. Mouse Ins1 promoter shows high specificity in pancreatic betacells without leakage in the brain.
(J:224637)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:224637 Cheng Y, et al., Generation and Characterization of Transgenic Mice Expressing Mouse Ins1 Promoter for Pancreatic beta-Cell-Specific Gene Overexpression and Knockout. Endocrinology. 2015 Jul;156(7):2724-31 |
| All: |
1 reference(s) |
|
Analysis Tools
