Ankfn1^em2Mnw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ankfn1^em2Mnw
• Name: ankyrin-repeat and fibronectin type III domain containing 1; endonuclease-mediated mutation 2, Mark N Wu
• MGI ID: MGI:6782846
• Synonyms: mWake^V5
• Gene: Ankfn1 Location: Chr11:89280918-89668727 bp, - strand Genetic Position: Chr11, 54.34 cM
• Alliance: Ankfn1^em2Mnw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: Using CRISPR/Cas9 genome editing, a V5 (GKPIPNPLLGLDST) epitope tag was fused to the C-terminus of Ankfn1 directly before the stop codon. (J:311969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ankfn1 Mutation: 48 strains or lines available

References

• Original: J:311969 Bell BJ, et al., Characterization of mWake expression in the murine brain. J Comp Neurol. 2021 Jun;529(8):1954-1987
• All: 2 reference(s)