Tg(Tek-Edil3)#Chav
Transgene Detail

Summary

• Symbol: Tg(Tek-Edil3)#Chav
• Name: transgene insertion, Triantafyllos Chavakis
• MGI ID: MGI:6781277
• Synonyms: EC-Del-1
• Transgene: Tg(Tek-Edil3)#Chav Location: unknown
• Alliance: Tg(Tek-Edil3)#Chav page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tek-Edil3)#Chav expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Edil3 (MGI:1329025)	"mouse promoter, mouse cDNA"

• Mutation details: The transgene insert contains the following elements: the mouse TEK receptor tyrosine kinase promoter (2.1 kb HindIII restriction segment including most of exon1), murine EGF-like repeats and discoidin I-like domains 3 cDNA, Tek enhancer sequence (1.7 kb XhoI-KpnI restriction fragment from inside 5' half of intron 1), and SV40 poly(A) signal sequences. This allele drives Edil3 expression in endothelial cells. (J:311776)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:311776 Kourtzelis I, et al., Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation. Thromb Haemost. 2016 Apr;115(4):781-8
• All: 4 reference(s)