Tg(CD68-MSR1)11Drg
Transgene Detail

Summary

• Symbol: Tg(CD68-MSR1)11Drg
• Name: transgene insertion 11, David Greaves
• MGI ID: MGI:6781268
• Synonyms: hSR-A III.1
• Transgene: Tg(CD68-MSR1)11Drg Location: unknown
• Alliance: Tg(CD68-MSR1)11Drg page

Transgene origin

• Strain of Origin: CBA x C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence, Modified isoform(s))
• Mutation: Insertion
• Tg(CD68-MSR1)11Drg expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MSR1 (4481)

  Msr1	(MGI:98257)

  "human promoter, human cDNA for type III isoform"

• Mutation details: The transgene contains the following elements: the human CD68 promoter and intron 1, sequence coding for a FLAG tag, in-frame with the cDNA for human type III membrane-bound macrophage scavenger receptor 1 isoform, and bovine growth hormone poly(A) signal sequence. (J:132589)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132589 Gough PJ, et al., The use of human CD68 transcriptional regulatory sequences to direct high-level expression of class A scavenger receptor in macrophages in vitro and in vivo. Immunology. 2001 Jul;103(3):351-61
• All: 1 reference(s)