Pten^tm2.1Ffur
Targeted Allele Detail

Summary

• Symbol: Pten^tm2.1Ffur
• Name: phosphatase and tensin homolog; targeted mutation 2.1, Frank Furnari
• MGI ID: MGI:6781263
• Synonyms: K125R-BL6
• Gene: Pten Location: Chr19:32734977-32803560 bp, + strand Genetic Position: Chr19, 28.14 cM
• Alliance: Pten^tm2.1Ffur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Single point mutation
• Mutation details: Targeting vector based on pKO scrambler V915 (Lexicon Genetics Inc., Woodland, TX) flanking a LoxP-pGK-Neo-LoxP selection cassette containing a BAC clone insertion containing intron 4, exon 5, and intron 5 of murine gene Pten (Gene ID 19211, NM 008960.2) with variant c.374A>G, p.Lys125Arg (K125R). (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Pten Mutation: 81 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)