Ggt5^em1Cys
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ggt5^em1Cys
• Name: gamma-glutamyltransferase 5; endonuclease-mediated mutation 1, Jason G Cyster
• MGI ID: MGI:6781226
• Gene: Ggt5 Location: Chr10:75425174-75453034 bp, + strand Genetic Position: Chr10, 38.55 cM
• Alliance: Ggt5^em1Cys page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 264 bp segment surrounding the start codon (ATG) in exon 1 was deleted by CRISPR/cas9 (CRISPR-EX) methodologies. (J:311846)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ggt5 Mutation: 26 strains or lines available

References

• Original: J:311846 Gallman AE, et al., Abcc1 and Ggt5 support lymphocyte guidance through export and catabolism of S-geranylgeranyl-l-glutathione. Sci Immunol. 2021 Jun 4;6(60)
• All: 1 reference(s)