Gt(ROSA)26Sor^{em1(CAG-Id2,-EGFP)Rbrc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(CAG-Id2,-EGFP)Rbrc}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, RIKEN BioResource Center
• MGI ID: MGI:6780027
• Synonyms: Rosa26^{LSL-Id2-IRES-H2B-EGFP}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(CAG-Id2,-EGFP)Rbrc} page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Inserted expressed sequence, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted a CAG promoter, floxed stop cassette, Id2 with a triple HA tag, IRES, and EGFP reporter gene with a histone (H2B) localization sequence. (J:308704)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:308704 Kiyokawa H, et al., Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9
• All: 1 reference(s)