Wfdc2^em1Jrgo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wfdc2^em1Jrgo
• Name: WAP four-disulfide core domain 2; endonuclease-mediated mutation 1, James Goldenring
• MGI ID: MGI:6771639
• Gene: Wfdc2 Location: Chr2:164404635-164410430 bp, + strand Genetic Position: Chr2, 85.2 cM, cytoband H3
• Alliance: Wfdc2^em1Jrgo page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2. (J:311110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wfdc2 Mutation: 17 strains or lines available

References

• Original: J:311110 Jeong H, et al., WFDC2 Promotes Spasmolytic Polypeptide-Expressing Metaplasia Through the Up-Regulation of IL33 in Response to Injury. Gastroenterology. 2021 Sep;161(3):953-967.e15
• All: 1 reference(s)