Tspo^tm1.2Hew
Targeted Allele Detail

Summary

• Symbol: Tspo^tm1.2Hew
• Name: translocator protein; targeted mutation 1.2, Wei He
• MGI ID: MGI:6765459
• Gene: Tspo Location: Chr15:83447793-83458404 bp, + strand Genetic Position: Chr15, 39.4 cM
• Alliance: Tspo^tm1.2Hew page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250785
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 2 and 3. (J:250785)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tspo Mutation: 18 strains or lines available

References

• Original: J:250785 Wang H, et al., Global Deletion of TSPO Does Not Affect the Viability and Gene Expression Profile. PLoS One. 2016;11(12):e0167307
• All: 3 reference(s)