Gper1^em1Wfro
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gper1^em1Wfro
• Name: G protein-coupled estrogen receptor 1; endonuclease-mediated mutation 1, Wei-Fang Rong
• MGI ID: MGI:6764549
• Synonyms: GPER^-
• Gene: Gper1 Location: Chr5:139408906-139413555 bp, + strand Genetic Position: Chr5, 78.58 cM, cytoband G1
• Alliance: Gper1^em1Wfro page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Using the CRISPR/Cas9 system a 17-bp deletion was introduced into the Gper1 gene. (J:310221)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gper1 Mutation: 27 strains or lines available

References

• Original: J:310221 Gao T, et al., G-Protein-Coupled Estrogen Receptor (GPER) in the Rostral Ventromedial Medulla Is Essential for Mobilizing Descending Inhibition of Itch. J Neurosci. 2021 Sep 15;41(37):7727-7741
• All: 2 reference(s)