Gt(ROSA)26Sor^{tm1(MYC/PEMT)Funai}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(MYC/PEMT)Funai}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Katsuhiko Funai
• MGI ID: MGI:6762170
• Synonyms: PEMTcKI
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(MYC/PEMT)Funai} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:299421
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Constitutively active, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(MYC/PEMT)Funai} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PEMT (10400)

  Pemt	(MGI:104535)

• Mutation details: A myc-tagged human PEMT cDNA with a preceding stop codon that was flanked with loxP sites were inserted into a Rosa26 locus. (J:299421)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:299421 Verkerke ARP, et al., Phospholipid methylation regulates muscle metabolic rate through Ca(2+) transport efficiency. Nat Metab. 2019 Sep;1(9):876-885
• All: 1 reference(s)