Pemt^tm1Funai
Targeted Allele Detail

Summary

• Symbol: Pemt^tm1Funai
• Name: phosphatidylethanolamine N-methyltransferase; targeted mutation 1, Katsuhiko Funai
• MGI ID: MGI:6762168
• Synonyms: PEMTcKO
• Gene: Pemt Location: Chr11:59861440-59937315 bp, - strand Genetic Position: Chr11, 37.81 cM
• Alliance: Pemt^tm1Funai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:299421
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites are inserted to flank the exon3 of the mouse Pemt gene by homologous recombination. (J:299421)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pemt Mutation: 17 strains or lines available

References

• Original: J:299421 Verkerke ARP, et al., Phospholipid methylation regulates muscle metabolic rate through Ca(2+) transport efficiency. Nat Metab. 2019 Sep;1(9):876-885
• All: 2 reference(s)