Itpr1^tm1.1Akino
Targeted Allele Detail

Summary

• Symbol: Itpr1^tm1.1Akino
• Name: inositol 1,4,5-trisphosphate receptor 1; targeted mutation 1.1, Akira Kinoshita
• MGI ID: MGI:6761813
• Synonyms: Itpr1-V5, Itpr1^V5
• Gene: Itpr1 Location: Chr6:108190057-108528070 bp, + strand Genetic Position: Chr6, 49.74 cM
• Alliance: Itpr1^tm1.1Akino page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:308935
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutation: Insertion
• Mutation details: The V5-tag sequence was inserted into the NaeI site adjacent to the stop codon in exon 62 of mouse Itpr1. The floxed Pgk-neomycin resistance gene cassette was removed by subsequent mating with CAG-Cre transgenic mice. (J:308935)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Itpr1 Mutation: 185 strains or lines available

References

• Original: J:308935 Kinoshita A, et al., Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells. Development. 2021 Aug 15;148(16):dev188755
• All: 1 reference(s)