Pbx1^em1Ucph
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pbx1^em1Ucph
• Name: pre B cell leukemia homeobox 1; endonuclease-mediated mutation 1, University of Copenhagen
• MGI ID: MGI:6761314
• Gene: Pbx1 Location: Chr1:167946933-168259839 bp, - strand Genetic Position: Chr1, 75.95 cM
• Alliance: Pbx1^em1Ucph page

Mutation origin

• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exon 1 produced a null allele. (J:310041)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pbx1 Mutation: 38 strains or lines available

Notes

This allele was generated in cells carrying Pbx1^em2Ucph.

References

• Original: J:310041 Mariani L, et al., A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm. Nat Commun. 2021 Aug 26;12(1):5136
• All: 2 reference(s)