Nsrp1^tm1.1Cdj
Targeted Allele Detail

Summary

• Symbol: Nsrp1^tm1.1Cdj
• Name: nuclear speckle regulatory protein 1; targeted mutation 1.1, Chang-Duk Jun
• MGI ID: MGI:6759471
• Synonyms: Nsrp1^f, Nsrp1^flox
• Gene: Nsrp1 Location: Chr11:76935118-76969261 bp, - strand Genetic Position: Chr11, 46.21 cM
• Alliance: Nsrp1^tm1.1Cdj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306261
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Two loxP sites and an FRT site flanked neomycin resistance gene cassette were inserted in or around the gene. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele. (J:306261)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nsrp1 Mutation: 48 strains or lines available

References

• Original: J:306261 Kim CH, et al., NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development. Nucleic Acids Res. 2021 Jun 4;49(10):5760-5778
• All: 1 reference(s)