Kdm6btm2.1(KOMP)Wtsi
Targeted Allele Detail
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Symbol: |
Kdm6btm2.1(KOMP)Wtsi |
Name: |
KDM1 lysine (K)-specific demethylase 6B; targeted mutation 2.1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:6758671 |
Synonyms: |
Jmjd3- |
Gene: |
Kdm6b Location: Chr11:69289334-69304501 bp, - strand Genetic Position: Chr11, 42.6 cM
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Alliance: |
Kdm6btm2.1(KOMP)Wtsi page
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IMPC: |
Kdm6b gene page |
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Mutant Cell Line: |
EPD0330_7_F03 |
Germline Transmission: |
Earliest citation of germline transmission:
J:306314
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Parent Cell Line: |
JM8A1.N3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 5536 starting at position 69291471 and ending at position 69297007 of Chromosome 11 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. The lacZ cassette was removed through subsequent flp-mediated recombination in allele Kdm6btm1(KOMP)Wtsi.
(J:306314)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Kdm6b Mutation: |
65 strains or lines available
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Original: |
J:306314 Maheshwari U, et al., Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. 2020 Jun 16;31(11):107767 |
All: |
1 reference(s) |
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