Prox1^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prox1^{em1(cre/ERT2)Smoc}
• Name: prospero homeobox 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6758048
• Synonyms: Prox1^{em1(IRES-CreERT2-pA)Smoc}, Prox1-IRES-CreERT2
• Gene: Prox1 Location: Chr1:189850232-189902911 bp, - strand Genetic Position: Chr1, 95.85 cM
• Alliance: Prox1^{em1(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Prox1^{em1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prox1 (MGI:97772)

• A IRES-CreERT2-pA expression cassette was knocked into the Prox1 gene stop codon site. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prox1 (mouse) Summary of all recombinase alleles driven by Prox1. Alliance mouse Prox1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prox1 Mutation: 43 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)