Stab2^tm1.2Isk
Targeted Allele Detail

Summary

• Symbol: Stab2^tm1.2Isk
• Name: stabilin 2; targeted mutation 1.2, In-San Kim
• MGI ID: MGI:6755513
• Gene: Stab2 Location: Chr10:86677062-86843889 bp, - strand Genetic Position: Chr10, 43.14 cM
• Alliance: Stab2^tm1.2Isk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236556
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was flanked by loxP sites. An FRT-flanked PGK-neomycin selection cassette was inserted between exon 2 and the second loxP site. Flp-mediated recombination removed the selection cassette and cre-mediated recombination deleted exon 2. (J:236556)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stab2 Mutation: 136 strains or lines available

References

• Original: J:236556 Park SY, et al., Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nat Commun. 2016 Mar 14;7:10871
• All: 2 reference(s)