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Sumf1em3Lutzy
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Sumf1em3Lutzy
Name: sulfatase modifying factor 1; endonulclease-mediated mutation 3, Cathy Lutz
MGI ID: MGI:6754178
Synonyms: Sumf1A277V
Gene: Sumf1  Location: Chr6:108083989-108162543 bp, - strand  Genetic Position: Chr6, 49.71 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Humanized sequence)
Mutation:    Nucleotide substitutions
 
Mutation detailsCRISPR/cas9 genome editing is used to introduce a A277V (GCC to GTA), missense mutation into exon 6. The mutation is orthologous to A279V in humans and is associated with multiple sulfatase deficiency (MSD). (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sumf1 Mutation:  24 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory