Cnr1^tm1Mars
Targeted Allele Detail

Summary

• Symbol: Cnr1^tm1Mars
• Name: cannabinoid receptor 1; targeted mutation 1, Giovanni Marsicano
• MGI ID: MGI:6750933
• Gene: Cnr1 Location: Chr4:33924593-33948831 bp, + strand Genetic Position: Chr4, 16.28 cM
• Alliance: Cnr1^tm1Mars page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306938
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP flanked STOP cassette and Cnr1 sequence lacking the first 22 amino acids replaced the wild-type coding sequence. (J:306938)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnr1 Mutation: 43 strains or lines available

References

• Original: J:306938 Soria-Gomez E, et al., Subcellular specificity of cannabinoid effects in striatonigral circuits. Neuron. 2021 May 5;109(9):1513-1526.e11
• All: 1 reference(s)