Nlrp10^tm1.2Arte
Targeted Allele Detail

Summary

• Symbol: Nlrp10^tm1.2Arte
• Name: NLR family, pyrin domain containing 10; targeted mutation 1.2, TaconicArtemis
• MGI ID: MGI:6740184
• Gene: Nlrp10 Location: Chr7:108521060-108529365 bp, - strand Genetic Position: Chr7, 57.21 cM, cytoband E3
• Alliance: Nlrp10^tm1.2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:298763
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted a loxP site and FRT-flanked neomycin resistance cassette upstream of exon 2 and inserted an F3 flanked puromycin resistance cassette and loxP site downstream of exon 3. Flp-mediated recombination removed both selection cassettes and left exons 2 and 3 floxed. Cre-mediated recombination removed exons 2 and 3. (J:298763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrp10 Mutation: 40 strains or lines available

References

• Original: J:298763 Mirza N, et al., NLRP10 Affects the Stability of Abin-1 To Control Inflammatory Responses. J Immunol. 2019 Jan 1;202(1):218-227
• All: 1 reference(s)