Pgam1^tm2.1Hiko
Targeted Allele Detail

Summary

• Symbol: Pgam1^tm2.1Hiko
• Name: phosphoglycerate mutase 1; targeted mutation 2.1, Hiroshi Kondoh
• MGI ID: MGI:6730300
• Synonyms: Pgam1^flox
• Gene: Pgam1 Location: Chr19:41900362-41907099 bp, + strand Genetic Position: Chr19, 35.44 cM
• Alliance: Pgam1^tm2.1Hiko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:306793
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT site flanked neomycin resistance gene cassette and a loxP site were inserted into intron 1 and a second loxP site into intron 4. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exons 2-4 floxed. (J:306793)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgam1 Mutation: 23 strains or lines available

References

• Original: J:306793 Mikawa T, et al., Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis. iScience. 2020 Jul 24;23(7):101306
• All: 3 reference(s)