Bap1^em4Test
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bap1^em4Test
• Name: Brca1 associated protein 1; endonuclease-mediated mutation 4, Joseph R Testa
• MGI ID: MGI:6730081
• Synonyms: Bap1^f
• Gene: Bap1 Location: Chr14:30973407-30981901 bp, + strand Genetic Position: Chr14, 19.09 cM
• Alliance: Bap1^em4Test page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Zinc finger nuclease technology was used to insert loxP sites in introns 6 and 7, creating a floxed exon 7. (J:278954)

Tumor Data

List all tumor models in MMHCdb carrying Bap1^em4Test

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bap1 Mutation: 34 strains or lines available

References

• Original: J:278954 Kukuyan AM, et al., Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models. Cancer Res. 2019 Aug 15;79(16):4113-4123
• All: 1 reference(s)