Stub1^em2Schiz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stub1^em2Schiz
• Name: STIP1 homology and U-Box containing protein 1; endonuclease-mediated mutation 2, Jonathan Schisler
• MGI ID: MGI:6729914
• Synonyms: CHIP^S20E
• Gene: Stub1 Location: Chr17:26049608-26051893 bp, - strand Genetic Position: Chr17, 12.93 cM, cytoband B1
• Alliance: Stub1^em2Schiz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting produced the amino acid substitution of serine with glutamic acid at position 20 (S20E). (J:296831)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stub1 Mutation: 21 strains or lines available

References

• Original: J:296831 Ranek MJ, et al., CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury. Nat Commun. 2020 Oct 20;11(1):5237
• All: 1 reference(s)