Sting1^em3Vnce
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sting1^em3Vnce
• Name: stimulator of interferon response cGAMP interactor 1; endonuclease-mediated mutation 3, Russell Vance
• MGI ID: MGI:6729712
• Gene: Sting1 Location: Chr18:35866732-35873607 bp, - strand Genetic Position: Chr18, 19.23 cM, cytoband B3
• Alliance: Sting1^em3Vnce page

Mutation origin

• Strain of Origin: BALB/cAnNCrl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 genome editing is used to create a 5 bp deletion (GCCTC; nucleotides 402-406) in exon 3. Immunoblot analysis of bone marrow macrophages demonstrates that no protein is produced. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sting1 Mutation: 49 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)