Tg(Runx3-tdTomato)Rbo
Transgenic Allele Detail

Summary

• Symbol: Tg(Runx3-tdTomato)Rbo
• Name: runt related transcription factor 3; transgene insertion, Remy Bosselut
• MGI ID: MGI:6729222
• Synonyms: Runx3^tRFP
• Gene: Runx3 Location: Chr4:134847963-134905301 bp, + strand Genetic Position: Chr4, 67.19 cM
• Alliance: Tg(Runx3-tdTomato)Rbo page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Using a BAC with recombineering, the tdTomato red fluorescent protein reporter cDNA was inserted into the 5' end of exon 2, downstream of the translation start site associated with the proximal promoter. The loxP site flanked neomycin resistance gene cassette that was also inserted was removed through subsequent cre-mediated recombination. (J:155097)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx3 Mutation: 28 strains or lines available

References

• Original: J:155097 Zamisch M, et al., The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus. J Exp Med. 2009 Nov 23;206(12):2685-99
• All: 3 reference(s)