Anxa10^{Tg(EEF1A1-lacZ)78-8Tyama}
Transgenic Allele Detail

Summary

• Symbol: Anxa10^{Tg(EEF1A1-lacZ)78-8Tyama}
• Name: annexin A10; transgene insertion 78-8, Tatsuro Yamamoto
• MGI ID: MGI:6729217
• Gene: Anxa10 Location: Chr8:62510076-62576184 bp, - strand Genetic Position: Chr8, 31.55 cM
• Alliance: Anxa10^{Tg(EEF1A1-lacZ)78-8Tyama} page

Transgene origin

• Strain of Origin: C57BL/6 x C3H

Transgene description

• Transgene Type: Transgenic (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Using a lacZ transgene driven by the human EEF1A1/EF1alpha promoter, a transgenic mouse line (line 78-8) was established by the transgene injection into 1-cell embryos. The genomic sequencing of the transgenic mouse revealed that both Spock3 and Anxa10 were disrupted simultaneously on chromosome 8 by the transgene insertions, resulting in double-null mutations of these genes. (J:308070)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Anxa10 Mutation: 27 strains or lines available

References

• Original: J:308070 Yamamoto A, et al., Structural abnormalities of corpus callosum and cortical axonal tracts accompanied by decreased anxiety-like behavior and lowered sociability in spock3- mutant mice. Dev Neurosci. 2014;36(5):381-95
• All: 1 reference(s)