Gabra4^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gabra4^em1Cya
• Name: gamma-aminobutyric acid type A receptor subunit alpha 4; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6729208
• Synonyms: Gabra4^em1Cgen
• Gene: Gabra4 Location: Chr5:71727092-71815651 bp, - strand Genetic Position: Chr5, 38.08 cM
• Alliance: Gabra4^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN-targeting of exon 1 deleted 8 bp. (J:304172)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabra4 Mutation: 42 strains or lines available

References

• Original: J:304172 Fan C, et al., Transcriptomics of Gabra4 knockout mice reveals common NMDAR pathways underlying autism, memory, and epilepsy. Mol Autism. 2020 Feb 7;11(1):13
• All: 1 reference(s)